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Observed performance metrics in laboratory models
Observed performance metrics in laboratory models
Research summary on S4 (also known as Andarine).
S-4 (Andarine) is a Selective Androgen Receptor Modulator (SARM)
S-4 (Andarine) is a Selective Androgen Receptor Modulator (SARM) — originally developed for muscle wasting and osteoporosis.
In research settings, it has been shown to:
✔ Increase muscle mass while reducing fat.
✔ Support bone density improvements.
✔ Enhance muscular definition and vascularity.
📊 BODY COMPOSITION:
S-4 is often studied for its ability to reduce fat mass while preserving or increasing lean muscle.
🛡️ BONE HEALTH:
Research shows positive effects on bone strength and mineral density.
⚡ AESTHETIC BENEFITS:
May enhance muscle hardness and vascularity in trained subjects.
1. Agarwal, Deepali, Kamath, Divya, Gregory, Steven T, & O'Connor, Michael (2015). Modulation of decoding fidelity by ribosomal proteins S4 and S5.. Journal of bacteriology.
https://doi.org/10.1128/JB.02485-14
2.Ahmed, R, & Fields, B N (1982). Role of the S4 gene in the establishment of persistent reovirus infection in L cells.. Cell.
https://doi.org/10.1016/0092-8674(82)90215-x
3.Ahn, Keun Soo, Han, Ho-Seong, Yoon, Yoo-Seok, & Cho, Jai Young (2011). Laparoscopic anatomic S4 segmentectomy for hepatocellular carcinoma.. Surgical laparoscopy, endoscopy & percutaneous techniques.
https://doi.org/10.1097/SLE.0b013e31822462c8
4. Alekov, A K, Peter, W, Mitrovic, N, Lehmann-Horn, F, & Lerche, H (2001). Two mutations in the IV/S4-S5 segment of the human skeletal muscle Na+ channel disrupt fast and enhance slow inactivation.. Neuroscience letters.
https://doi.org/10.1016/s0304-3940(01)01895-x
5. Allen, P N, & Noller, H F (1989). Mutations in ribosomal proteins S4 and S12 influence the higher order structure of 16 S ribosomal RNA.. Journal of molecular biology.
https://doi.org/10.1016/0022-2836(89)90509-3
6. Arhem, Peter (2004). Voltage sensing in ion channels: a 50-year-old mystery resolved?. Lancet (London, England).
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