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Observed performance metrics in laboratory models
Observed performance metrics in laboratory models
Research summary on S23
S-23 is a Selective Androgen Receptor Modulator (SARM)
S-23 is a Selective Androgen Receptor Modulator (SARM) — notable for its high binding affinity and potential as a male contraceptive in research.
In research settings, it has been shown to:
✔ Increase lean muscle mass.
✔ Enhance strength output.
✔ Suppress fertility in male research models.
⚡ POTENT ANABOLIC EFFECTS:
S-23 has demonstrated significant anabolic activity in skeletal muscle.
📈 STRENGTH ENHANCEMENT:
Research subjects have shown measurable gains in maximal force production.
🚫 FERTILITY SUPPRESSION:
Acts on the hypothalamic-pituitary-gonadal axis to reduce sperm production in animal models.
1.Alhalabi, Hana, Korsmeier, Linus, Thomas, Andreas, & Thevis, Mario (2025). Investigations Into the Urinary Metabolite Elimination Profile of the Selective Androgen Receptor Modulator S-23 in Studies Mimicking Contaminated Product Ingestion for Doping Control Purposes.. Biomedical chromatography : BMC.
https://doi.org/10.1002/bmc.70090
2.Ameline, Alice, Gheddar, Laurie, Raul, Jean-Sébastien, & Kintz, Pascal (2022). In vitro characterization of S-23 metabolites produced by human liver microsomes, and subsequent application to urine after a controlled oral administration.. Journal of pharmaceutical and biomedical analysis.
https://doi.org/10.1016/j.jpba.2022.114660
3.Baptiste-Okoh, Nicole, Barsotti, Anthony M, & Prives, Carol (2008). A role for caspase 2 and PIDD in the process of p53-mediated apoptosis.. Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.0711800105
4. Beathard, Chase, Mooney, Sutton, Al-Saharin, Raed, Goyer, Aymeric, & Hellmann, Hanjo (2021). Characterization of . Frontiers in plant science.
https://doi.org/10.3389/fpls.2021.629208
5. Beekman, Jeffrey M (2016). Individualized medicine using intestinal responses to CFTR potentiators and correctors.. Pediatric pulmonology.
https://doi.org/10.1002/ppul.23553
6. Burkle, Christopher (2015). S23. The Father (and Lawyer) of Intravenous Therapy.. Journal of anesthesia history.
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