Role Overview
A Protein Scientist leads the discovery, design, expression, purification, and characterization of proteins to support research and development in areas such as therapeutics, enzyme engineering, and structural biology.

Key Responsibilities

• Design and clone expression constructs for target proteins, optimizing codons and fusion tags as needed.
• Develop and implement protocols for protein expression in bacterial, yeast, insect, or mammalian systems.
• Purify proteins using chromatographic techniques (e.g., affinity, ion-exchange, size-exclusion) and assess purity via SDS-PAGE and Western blot.
• Characterize protein function and stability through biophysical and biochemical assays (e.g., enzyme kinetics, binding studies, thermal shift).
• Troubleshoot expression and purification bottlenecks, optimizing yields and bioactivity.
• Collaborate with structural biology, assay development, and bioinformatics teams to advance protein targets toward preclinical applications.
• Maintain detailed laboratory records, analyze experimental data, and present findings in written reports and internal meetings.

Qualifications & Skills

• PhD (or MS with extensive industry experience) in Biochemistry, Molecular Biology, Protein Engineering, or related field.
• Hands-on expertise in recombinant protein expression systems and purification workflows.
• Proficiency with analytical techniques such as HPLC/UPLC, mass spectrometry, circular dichroism, and dynamic light scattering.
• Strong aptitude for assay development, data analysis, and experimental troubleshooting.
• Excellent communication and teamwork skills, with the ability to translate complex results for cross-functional stakeholders.
• Familiarity with laboratory information management systems (LIMS) and adherence to safety and quality standards.

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