S (Selective) A (Androgen) R (Re uptake) M (Modulators). They do just that; Selecting specific (bone and muscle) Androgen receptors as opposed to organ and prostate (the bad kind) Re up taking those which causes a continuous communication between muscle cells and the signals from the brain and other systems to tell them “grow”. The Modulation is exerted by this influence of protein synthesis.
This is why they were created. By researchers who noticed the need for kids and women who had muscle wasting/degenerative diseases. Given traditional testosterone and like compounds, the obvious side effects arose in these populations, so hence the (muscle tissue and bone specific Selectivity) of SARMS was made.
There’s specific SARMs for specific outcomes. All of them, exerting their effects via those Signals. Cardarine and SR9009 sends the “cardiac pulses” that tells the heart to “pump more effectively”, the lungs, to “maximize oxygen capacity”. Mk677 to pulse the Pituitary gland to “release more growth hormone” and block bad hormones that block growth hormone. RAD140 and Ligandrol to decrease cortisol (and other anti catabolic hormone) production. Doing so by 60-70%. To increase calcium deposits in bones, making them stronger. To increase exogenous testosterone. Amongst others. YK11 to decrease the regulator in the body that limits muscle growth; Myostatin. To increase the Follistatin; a de regulating protein that increases anabolism. S4 and S23 by signaling the metabolism via several mechanisms to “burn more fat”. Etc.
So in layman’s terms, they’re communicators. Linguists/negotiators for the muscles/bones to other body systems and functions.
